Assuntos
Anti-Inflamatórios/administração & dosagem , Anticorpos Monoclonais/administração & dosagem , Doença de Crohn/complicações , Doença de Crohn/diagnóstico , Fármacos Gastrointestinais/administração & dosagem , Síndrome de Melkersson-Rosenthal/tratamento farmacológico , Síndrome de Melkersson-Rosenthal/etiologia , Adolescente , Doença de Crohn/tratamento farmacológico , Feminino , Humanos , Infliximab , Perfusão , Resultado do TratamentoRESUMO
Collagenous colitis belongs to the group of microscopic colitis. The aetiology and pathogenesis are unknown but different pathogenic hypothesis, autoimmune, infectious, alimentary and medicinal being are advanced, the last one being the most frequent aetiology. The collagenous gastritis is a rare entity and its association with collagenous colitis was exceptionally reported, only six cases being published. We report the seventh case of collagenous gastritis, ileitis and colitis in a 75-year-old woman with chronic diarrhea and important weight loss. This thickened subepithelial collagen band was appeared in an autoimmune injury context with antecedent of Hashimoto's thyroiditis and probably chronic atrophic Biermer's gastritis. The clinical and histological evolution was favourable with budesonide.
Assuntos
Anti-Inflamatórios/uso terapêutico , Doenças Autoimunes/tratamento farmacológico , Budesonida/uso terapêutico , Colite Colagenosa/tratamento farmacológico , Gastrite/tratamento farmacológico , Ileíte/tratamento farmacológico , Idoso , Doenças Autoimunes/metabolismo , Colite Colagenosa/complicações , Colite Colagenosa/imunologia , Colágeno/metabolismo , Feminino , Mucosa Gástrica/metabolismo , Mucosa Gástrica/patologia , Gastrite/complicações , Gastrite/imunologia , Gastrite/metabolismo , Doença de Hashimoto/complicações , Humanos , Ileíte/complicações , Ileíte/imunologiaRESUMO
Filiform polyposis or giant inflammatory polyp is an uncommon benign lesion that has principally been reported in patients with evidence of inflammatory bowel disease, Crohn's disease or ulcerative colitis. It appears to be a sequella of diffuse mucosal inflammation. More rarely, PF found in association with colonic non specific inflammation. PF has rarely been reported in patients without previous colonic disease. We report the case of a 60-year-old woman without history of colonic disease who presented a PF revealed by hematochesia.
Assuntos
Pólipos do Colo/diagnóstico , Hemorragia Gastrointestinal/etiologia , Pólipos do Colo/complicações , Pólipos do Colo/cirurgia , Colonoscopia , Feminino , Seguimentos , Humanos , Pessoa de Meia-Idade , Reto , Fatores de Tempo , Resultado do TratamentoRESUMO
Cytomegalovirus (CMV) infection of the gastrointestinal tract occurs mainly in immunosuppressed patients. We report here the case of a 76-Year-old woman, without obvious cause of immunosuppression, who developed severe proctitis. The clinical course was favourable with ganciclovir therapy. In the absence of controlled data in the field of CMV intestinal infections in immunocompetents, we discuss the potential benefit of an antiviral therapy in those patients who do not recover rapidly and spontaneously.
Assuntos
Infecções por Citomegalovirus/diagnóstico , Proctocolite/diagnóstico , Proctocolite/virologia , Neoplasias Retais/diagnóstico , Doença Aguda , Idoso , Infecções por Citomegalovirus/imunologia , Diagnóstico Diferencial , Feminino , HumanosAssuntos
Colite Isquêmica/induzido quimicamente , Indóis/efeitos adversos , Piperidinas/efeitos adversos , Agonistas do Receptor de Serotonina/efeitos adversos , Vasoconstritores/efeitos adversos , Feminino , Humanos , Pessoa de Meia-Idade , Transtornos de Enxaqueca/tratamento farmacológico , TriptaminasRESUMO
Hepatocellular carcinoma is a malignant tumor with a poor prognosis, particularly when it is unresectable. The results of tamoxifen treatment in hepatocellular carcinoma have been disappointing and randomized studies have shown conflicting results. We report the case of a 72-yr-old-man with histologically confirmed hepatocellular carcinoma on a normal liver, that regressed with tamoxifen treatment. Regression was confirmed by normalization of serum alpha-fetoprotein levels and a significant decrease in radiological lesions by 66%. The patient was alive in excellent clinical condition more than 30 months after the initial diagnosis.